MyBioSource.com's SAP30 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The SAP30 Antibody was generated using SAP30 as the antigen and it reacts with Human, and Mouse.
Description
Function: Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones.
Subunit Structure: Interacts with SIN3A, SIN3B, HDAC2 and NCOR1. Interacts with SAMS1. Component of the histone deacetylase complex that includes at least SIN3A, HDAC1 and HDAC2 (By similarity). Interacts with HDAC1 (PubMed:9651585). Interacts with HCFC1 (PubMed:12670868). Found in a complex composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1 (By similarity).
Similarity: Belongs to the SAP30 family